Weight Loss Drugs May Enhance Taste Sensitivity, Especially for Sweets

Weight Loss Drugs May Enhance Taste Sensitivity, Especially for Sweets

A recent study from the University Medical Centre in Ljubljana, Slovenia, has found that semaglutide, the active ingredient in the diabetes and obesity drugs Ozempic and Wegovy, can significantly influence taste perception and brain responses to sweet foods. Led by Mojca Jensterle Sever, the research revealed that women taking semaglutide showed increased sensitivity to sweet tastes compared to those taking a placebo. The study was presented at the Endocrine Society's annual meeting in Boston.

Participants taking semaglutide also exhibited changes in gene expression in the tongue, which are linked to taste perception, and alterations in brain activity in response to sweet stimuli. These findings suggest that the drug may aid weight loss not only by reducing appetite and slowing digestion but also by enhancing taste sensitivity, potentially decreasing the desire for high-calorie, sweet foods. Further research is planned to explore the implications of these findings and their potential applications in treating obesity.

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