Paxlovid 15-Day Regimen Shows No Clear Benefit for Long COVID, Study Finds

Paxlovid 15-Day Regimen Shows No Clear Benefit for Long COVID, Study Finds

A clinical trial conducted by Stanford Medicine has found that a 15-day course of Paxlovid, an antiviral drug targeting SARS-CoV-2, does not significantly alleviate symptoms of long COVID. The study, which involved 155 participants, showed no substantial improvement in symptoms such as fatigue, brain fog, shortness of breath, body aches, or gastrointestinal and cardiovascular issues. Despite this, the trial confirmed the safety of an extended-duration Paxlovid treatment.

Published in JAMA Internal Medicine, the findings indicate that while Paxlovid is safe for extended use, it does not reduce long COVID symptoms. Researchers, including Dr. Upinder Singh, suggest that further studies might explore the efficacy of different dosages or treatment durations, or focus on patients with specific symptoms or those who have been ill for shorter periods. Pfizer has stated that these results will not affect their ongoing collaborative studies of Paxlovid as a potential COVID-19 treatment.

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