Eli Lilly's Weight Loss Drug Cuts Diabetes Risk by 94% in Long-Term Trial

Eli Lilly's Weight Loss Drug Cuts Diabetes Risk by 94% in Long-Term Trial

Eli Lilly's weight loss drug, tirzepatide, has shown promising results in reducing the risk of developing type 2 diabetes by 94% in obese or overweight adults with pre-diabetes. This data comes from a three-year follow-up of the late-stage trial known as SURMOUNT-1. The study, which included over 1,000 participants, also indicated significant sustained weight loss. Adults on the highest weekly dose of the drug experienced an average weight reduction of 22.9% over 176 weeks, compared to a 2.1% decrease for those on a placebo.

The findings suggest that tirzepatide, marketed as Zepbound for weight loss, could potentially delay the progression to diabetes in high-risk individuals. Eli Lilly plans to submit these results to a peer-reviewed journal and present them at an upcoming medical conference in November. The safety profile of tirzepatide remained consistent with previous studies, according to Jeff Emmick, Lilly's senior VP of product development. The company is also exploring the extension of its obesity drugs to treat related conditions such as sleep apnea and heart disease.

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